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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49bcd4a70926a52569f6337e02dc01f82b27dff1e4d72a903162a3b4dbcfede3' 
  AND token = 'X0HHI6bOBFe8JOkH0XcQdtSvGKR/Nug7YfU0BfZL4hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}