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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5b952b9f276a81a5a44cd3c3a4d4f2e5cc7d49ebb94cbc0e3df9aac4467a37' 
  AND token = 'VBzse7vRiNbudJoOWXnnvW5355d2BIpojigw/0OfOUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}