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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '222ef7c484a77e2492f12a5de12a13dfb388d54ab7549c3f1468d7999ad4e330' 
  AND token = 'CvOKZnEVPM24CfJYpeU12HiURtquiTkMdqqDTy7m4ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}