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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa95493be1bc678331509d266e69deba713353c5f2d63e74959cf5f5badb0bb' 
  AND token = 'Qn2QIqW+7TtfRcrf7wM7cdLA6fFU5qFNVPWHjaOCQ2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}