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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3328fd17fd814560b0182bf6d99798f602329db8e018122667490a35b04a92fe' 
  AND token = 'DjK0Af7KuOu+2N+EzUKt89anyVuzpw4AKrB3Dfrq9VE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}