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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '544875701bdb47e021deccc428f3b1bede21562929f81463fe530716ce255920' 
  AND token = '6FEE0ai+ITHriwbEWa97I7VcTnI7QrEyogntx2Dj50w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}