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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddb5b68b1155b44aa9fdd53c852f15d04178a7636fc81adcd581c2d01bc4519e' 
  AND token = 'C49f5+v6T4Zo+G0jEisMkSSuYu40MmKz0Y3BLMDSuTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}