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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49e312ffdd27defd882bdebcebcd7a894e3e5cf03561401a4f4b3035413337c' 
  AND token = '6We9nS0DWHPuq66WWIJGpwBZoBCM0cipu7YRjssUGwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}