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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f20171295417da7ff9a293e2494d2315886367b5a52b3207f9ce0ef3d1c94abb' 
  AND token = '+yX42WPna6Jhiow/SyyIz9WPp5Vgkf+JE/k4i+H4NuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}