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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceabc7801afc0218a0062ce1d7f1c7797bc1cac2fa856c1df9db1849d770d36f' 
  AND token = 'IqsdHQuEo5MJFtj/GJIfRDESERVmbunhPy64Rj9rWRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}