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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81f6f53fac7daeed394ed7b76c289c2647eb432ad8bb9539b88045412fd353b3' 
  AND token = 'k2wP1e3KJW5eAnadqlVa3qiA2HmzWkH9PcmeVajtMc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}