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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee5b421bab9de6403b9cee5bb6b9fda6539c09eaa0c0f68efd84875f6378b67' 
  AND token = 'NUCGCRGeZ697DLpaxKzpZToho03NNOKGjKLMgBOqaEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}