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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd8b065bd43f44eca9a1ac32d3b8aa5f65598a55b5b72df9eca9bb1d91fd57c' 
  AND token = 'yAUphC0IZsKmKRFNGoaLpFyHvJHEQzt7/F6LBEa2wUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}