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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8014fa19baf28b9bcd58f8d125fff4c3665c9fb4cfefe21d13f8a88eb554a41' 
  AND token = 'XP1rrJe1eftwZmJ6v+cP/OP/ASaYJOtKz5pCV+CIrIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}