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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f2f04649be85038256cb9e4d4cc9498dcd2f4d7d0f2993b7802c9071da344c' 
  AND token = 'ytFf4DnkWOuEDi80fyZVLGLH78XyD0uaITDGzu6rdw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}