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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4e7ff0a80b6c4432e9780daa45a117c0f6366e68ed8852f422507e045393c48' 
  AND token = 'wjzVXgNeUNIohBJ5D9rzEEo0miYnBDkOjnPPBms5O50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}