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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f41900dab8efb839b09ce8dbb5ee94e5adec52742490e398f50c875e1d864774' 
  AND token = '46qr5Ye01cOsquqgiOfs1LNlUv6k98MZ/PRpkbLjBKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}