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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5217342712c6cbb26c5a4f78ce846c3a852d03a29a6fd2541d1d41848561aaae' 
  AND token = 'eNc5qGbkuB79b6mLqCLT5nLxW5xGVRD7xDSIc71Rzyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}