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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5054ed9b0e11b90bfdd612881b402399fd671963208967e37c22017adc19af05' 
  AND token = 'tz0khRYR6roL/igxC1I6k/ylUdZi8D7556/BT0kFfCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}