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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7169785e8d41845407f77a1df82ae9725af417a4e245c18331f5389bb6ff9c52' 
  AND token = 'XbUUUmExHGuO6tQVsbj9VHt6ZcaRWoKEvUELZiTMlXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}