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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ec8426d9100fb71d9196ed6e408ec9084dea66b7ec8c7ea24729a1a1f8a2251' 
  AND token = 'eOZSEBjhiHayUUKIRAb9PnzTxcb/lGcNFbWFPDSgyPI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}