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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03e4dc6ea7360631832de3c6d4c79935408a2b7d5e88bd579133f0acb0dff68b' 
  AND token = 'asVLFQvA5M2FpUyaYT2UXDB9nXmQrtE8T7Zl67FqTzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}