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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66600d12b0917e8ab99cc21d66f62e0c1e27e2e59bd7ba72e741814175d0f3f3' 
  AND token = 'IX1vk/hBkKx2m7k3MBYEyeaOsx0XQ89jNLjd1FWRzfs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}