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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161e2a21975dc330848cb9d4f25503a4a8460c2a64b34d6576db8e956358aca0' 
  AND token = 'HjlS9YNrjX8SVU9NVGRmQ6sqUOq4sti5FqrRZSAT5+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}