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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e218d95c57bde7e02112505be315029165dc532a5e87a0269d9c9ff7de557190' 
  AND token = 'iku9GLMvuWyZxVAIMtfL7fu+9geNpMoYqxEc4hkdUjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}