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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14fe47774fc35a82a78bca45dc4f8ac75507a445b0d8b12191a62187871083b1' 
  AND token = 'SkytqaJ601f3F+MBYSXgySV1x0TsroR3oymdQ9IOan4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}