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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8260b20887c994220bdf889509e38a2f571d211608b9cb6c6e9f51d30add856e' 
  AND token = 'w7L9+KEPwR0px5U0bfbLaqDFJw8wIA12rj2IgFxMhjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}