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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb9d0a15d5821249651780daf0e24eea3ba86f235db27226ed8d651ea24c99a2' 
  AND token = 'MHQuCGZZItEQLssYssxnKAMaMv6x37DEzbI6AX7nag4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}