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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8eae8f2c1defb894db91f47e2997935fb174d7b181eb146ec5336890c10160' 
  AND token = 'YCvkxZeG33M7Tu/UJRl8m0lV7fSQ5nXwmn8CDnn1IRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}