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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8139cacd145423b787c89835a35a20b4b88a27f0274f1c5a9eac9435164f2e79' 
  AND token = '8u+A1p/D7bKHq3zcrF6xI9L9LPFNWCYtHPTK43+EXb0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}