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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5eeedd02b8c19201825adf14c0b309d1fa34e20699f1c5bb8618694dc1fd4f8' 
  AND token = 'qactamO0vgCFYJ1KHCKEUQ5pmGu8c1OZpZU60d+LSmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}