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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a11ca108f67f5e9df477bbd2f2eaec42e0195c49179b1838500decb62e49f6' 
  AND token = 'xMT3ha8Gh+E13dR4L/RfhRrC8pmbq8ItOtwuhwjs9A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}