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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b613a505d1f9c8770c77f804f3224e05b2d246466d42d41dd18b717ac6d18d6' 
  AND token = 'U3K77AJ5Rq9+oHpKWDNxQ5eWkneldQlDvhluBBBl0Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}