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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05d36ccbce7ce7fbd1f2d2198af5f0d5e9608eed10a89e528dd9d90193eb2497' 
  AND token = '46y+t/XDc7hgT1UdANnOBIpq63bufLJB7VP78CZ+2Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}