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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1542196bc405e1a00e1cc6191549710e7417de796eaf3e7d7d8180b78e3d81d5' 
  AND token = 'HMsZaDL4l+Ww+6tzLhjRQ3D6o5IdVZvtkAHRvh2VDrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}