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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '161d31e52f87ae09aec7062d4a4487edb30ac2066bc1ea184b64ba83ff7914fe' 
  AND token = 'Y5HcJnBmQV+9dGhQpb6X17XKeYASkkFhwAbRMf+d2EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}