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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1c4337d7b82c4492c866259eec337fab2023e712c000cba9ed5c3124636e70b' 
  AND token = 'Ymfp5Ye7L2s+IkoTeDMbZXFFQyeqJjAGhA4vWRLx5/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}