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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219d1b9dd2c03a78beb63241618c975496d793c026034f483380339d50ac196e' 
  AND token = 'HAn7ZZwwBt15rWql8GmqIjyHUCmpA0QDvdBA7fPLESA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}