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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea195527d149a4bd9fa7aeb44db0440f902d635a66cdb89af30cf2d06c9d30e' 
  AND token = '3T2BN57KdBYEVCyNL8zP0MfZkAyrXk1CnK/pvaYzbr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}