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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a95033fc65be1194ced96810fcd5104421f9d8d0010b19405b960359189136fb' 
  AND token = 'JXMrRcDRaeToX5rr8QasAOe+zUchElQ09hNcRvAT1D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}