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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e53db968aa1f631e2bd5860431afb9a3c35a27f211e3943a9958ee3a99787ea' 
  AND token = 'me/uLKZ1ciWqdyqZWFbEiv626NDOzaQlhMkPfz1irjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}