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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86a2c98c51a2e1221868d7a0b1d65e1ab5647068ed41322ccfa99c6e237dfb04' 
  AND token = 'kpIjX1tD9n9tQSpWzgwOnTDNsSwvhxxl2rA3tPJyYiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}