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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca8e013b5de4b4cec51339f74c30c308672b28109f0a6b5bc7d39dbe2cde335a' 
  AND token = 'PiD4Qxp4ynDtilMrN93S8ZT6bIayOJaX2yPBUwoxh6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}