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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '813bc204f52cd9aec1a0bf502c290973e4be54f461d9e229cc75d0c1c2165b4a' 
  AND token = 'O5Vs6OQX0gC2ofbi4kHEwg/pnVAql8ln+yxDm1Ozxyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}