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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f2460e55b08a779f850c8d3ef0fcfb53302435527610cdb70b39ec5531aec0' 
  AND token = 'evj5huWb3MzRcR6xm6DZYSuQo+NtxAdROTSmZk0m1dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}