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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '248143c1d3d31e558b7528d09377ad35839f530d5f44021471ba8ce6344b3bf6' 
  AND token = 'ecAmurt32zCc49jGVU0F3bCLY0jrbTB5M4aEBMzXTZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}