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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2e606f6b1bc06a0071fbcca9f4a10b34e0bb78e33a95d684f48e68aa912edfa' 
  AND token = 'fsTfEHLGuqC6k8e3JGX5EHXH4ps8NVTCZjZrOB4Jt24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}