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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da51d665367b103d9a1e89872eaaeba1e602e1fdc9078f15e50987d50250397' 
  AND token = 'lyovlGc45mb2wUWdrlA619BP3Tv8otX6aLsPOKCpc54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}