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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2415adba70740fe48ed6d643d8091f3b6e019ab34b301b0d7d678f4166c45221' 
  AND token = 'r/7VYtN15/K98j1Cx2mLZxn/nlJg4mk8Zcp6yP9wgE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}