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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '794c054e0dc2d9940dce16c5be9ededf1ff6d13e4760d0640b9000d615e665a4' 
  AND token = 'nkUpyhMd7J8cxDXcDaKSYG/R34V07CTiscmcaCNrlU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}